We provide custom coating services in bioanalytic, biomedical, and biomaterial fields. The coatings attain the desired surface properties: biocompatibility, chemical functionalization, biomolecular (protein, antibody, enzyme, polypeptide, DNA, etc.) immobilization,
anti-fouling, anti-agglutination, and lubrication. The substrates include glass, silicon, quarts, mica, noble metals, and plastics. Here are some examples of our services,
- Coat custom sizes of substrates with required functional groups and desired thickness.
- Wide range of choices of coating materials from natural to synthetic polymers.
- Application oriented coating of specific biomolecules including protein, enzyme, antibody, and DNA
- Super hydrophilic surface that can keep cells/proteins in water without using extra water reservoir for microscopy scan.
- Coat the internal walls of microfluidics and lab-on-chip channels with bioinert material to reduce biofouling.
- Modify the probing surface of any shape in all types of optical and electrochemical biosensors.
- Non-fouling coat on membrane and filter
- Biocompatible coating on various biomedical devices including catheter, guide wire, implants, and intraocular lens to reduce immune rejection, thrombosis, allergy and friction.
Most hydrophilic surfaces are biocompatible and non-fouling. Here are some differences between our novel coating technology and products from other companies (use general plastics as substrate).
| Other companies | Sofchip |
|---|
| Water contact angle greater than 30o | Water contact angle less than 30o |
| Coating thickness greater than10 micrometer | Coating thickness less than 0.01 micrometer |
| Base coating contains harmful compounds (e.g., polyurethane and organic solvent) | Hydrogel coating, no harmful compounds |
| Cannot withstand harsh environment (e.g., organic and alkaline solvents) | Withtand harsh environment |
| Low portion of covalent bonds holding the coating | High portion of covalent bonds holding the coating |
Please note that the durability of our coating depends on the application and storage environment. The coating on plastics from Sofchip can retain the hydrophilic property for up to years; while the hydrophilic property made through traditional etching method can last for only one day. Due to the ultra thin nature of the thickness, our coating is susceptible to mechanical scratching.
