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Surface plasmon resonence (SPR) sensor chips are high quality glass chips coated with a thin gold layer through vacuum deposition. These chips are functionalized with chemical groups for biomolecular (protein, antibody, enzyme, polypeptide, DNA, etc.) immobilization. The sizes of these chips are currently available for Biacore, Reichert Technologies, Bionavis, BiosensingUSA, Biosuplar and most home-made SPR instruments. All chips are packaged in inert gas. These chips are stand along and are not mounted on plastic substrate at this time (please send us a message for mounted chips). Please click here for how to replace the chip on the original mounting plastics. All biochips are manufactured on a per order basis. Each package contains three pieces of chips. All listed prices are for per package and in USD.

Bare gold SPR chips,non-functionalized gold coated plate

DescriptionCatalog NoSizePackPriceQty
Bare gold SPR chip1000002-39x9x0.3mm3 pcs$60

Carboxylate functionalized SPR chips carry negative charge in buffer with pH greater than 4. They covalently bind to biomolecules with primary amine groups after EDC/NHS activation. This binding is more efficient than aldehide-amine binging. Polyethylene glycol (PEG) is monofunctional polymer that is well known for resisting non-specific adsorption. Polysaccharides (dextran and arginic acid) have long and bulky chains. Synthetic polymers (SP) have long and slim chains. SP type I is highly negatively charged polymer due to high density of carboxylate. SP type II is mildly negatively charged polymer. SP type III has long spacer arms that extend the carboxylate groups away from the main chains.

DescriptionCatalog NoSizePackPriceQty
Carboxylated PEG SPR chip, basic 1121112-39x9x0.3mm3 pcs$105
Carboxylated PEG SPR chip, stablized1391122-39x9x0.3mm3 pcs$195
Caboxylated dextran SPR chip, thin 1511122-39x9x0.3mm3 pcs$165
Caboxylated dextran SPR chip, thick 1511132-39x9x0.3mm3 pcs$195
Arginic acid SPR chip, thin 1561122-39x9x0.3mm3 pcs$165
Caboxylated Synthetic polymer I SPR chip, thin 1311122-39x9x0.3mm3 pcs$165
Caboxylated Synthetic polymer I SPR chip, thick 1311132-39x9x0.3mm3 pcs$195
Caboxylated Synthetic polymer II SPR chip, thin 1321122-39x9x0.3mm3 pcs$165
Caboxylated Synthetic polymer II SPR chip, thick1321132-39x9x0.3mm3 pcs$195
Caboxylated Synthetic polymer III SPR chip, thin1331122-39x9x0.3mm3 pcs$165
Caboxylated Synthetic polymer III SPR chip, thick1331132-39x9x0.3mm3 pcs$195

Amine functionalized SPR chips carry positive charge in buffer with pH less than 10. They covalently bind to biomolecules with EDC/NHS activated carboxyl groups.

DescriptionCatalog NoSizePackPriceQty
Amine functionalized polymer SPR chip, thin 1344122-39x9x0.3mm3 pcs$165
Amine functionalized polymer SPR chip, thick1344132-39x9x0.3mm3 pcs$195
Chitosan SPR chip, thin1544122-39x9x0.3mm3 pcs$165

Epoxide functionalized SPR chips covalently bind to thiol,amine, hydroxyl, and other nucleophilic groups. The reaction with hydroxyl groups requires high pH and takes more than 12 hours.

DescriptionCatalog NoSizePackPriceQty
Epoxide functionalized polymer SPR chip, thin1511422-39x9x0.3mm3 pcs$165
Epoxide functionalized polymer SPR chip, thick1511432-39x9x0.3mm3 pcs$195

Maleimide functionalized SPR chips covalently bind to thiol groups (-SH). This reaction is very specific and fast.

DescriptionCatalog NoSizePackPriceQty
Maleimide functionalized polymer SPR chip, thin 1516422-39x9x0.3mm3 pcs$225
Maleimide functionalized polymer SPR chip, thick1516432-39x9x0.3mm3 pcs$255

Disulfide functionalized SPR chips covalently bind to thiol groups (-SH) through thio-disulfide exchange. After binding, the new formed disulfide bond can be broken by another thiol compound.

DescriptionCatalog NoSizePackPriceQty
Disulfide functionalized polymer SPR chip, thin 1512622-39x9x0.3mm3 pcs$225
Disulfide functionalized polymer SPR chip, thick1512632-39x9x0.3mm3 pcs$255

Ni complexed SPR chips bind to his-tagged proteins.

DescriptionCatalog NoSizePackPriceQty
Ni chelated SPR chip, thin 1513522-39x9x0.3mm3 pcs$255
Ni chelated SPR chip, thick1513532-39x9x0.3mm3 pcs$285

UV-initiator modified SPR chips covalently bind to all biomolecules under ultraviolet illumination. The reaction does not rely on any chemical groups on the biomolecules. It takes about 15 minutes under 100W UV lamp.

DescriptionCatalog NoSizePackPriceQty
UV initiator I modified SPR chip, thin 1517522-39x9x0.3mm3 pcs$195
UV initiator I modified SPR chip, thick1517532-39x9x0.3mm3 pcs$225

Protein A immobilized SPR chips bind to immunoglobulins, especially IgG.

DescriptionCatalog NoSizePackPriceQty
Protein A immobilized SPR chip, thin 1770122-39x9x0.3mm3 pcs$255
Protein A immobilized SPR chip, thick1770132-39x9x0.3mm3 pcs$285

Streptavidin immobilized SPR chips bind to biotin-labeled biomolecules.

DescriptionCatalog NoSizePackPriceQty
Streptavidin immobilized SPR chip, thin 1770522-39x9x0.3mm3 pcs$255
Streptavidin immobilized SPR chip, thick1770532-39x9x0.3mm3 pcs$285


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